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DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

Mouse thymidine kinase-negative (TK-) L cells were transformed with concatenates of cloned herpes simplex virus 1 TK DNA and different rabbit beta-globin DNAs in which the globin genes were preceded by native flanking sequences of 14, 66, 76, 425, and 1500 nucleotides.l In all cases, selection for T...

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Autors principals: Dierks, P, van Ooyen, A, Mantei, N, Weissmann, C
Format: Artigo
Idioma:Inglês
Publicat: 1981
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC319140/
https://ncbi.nlm.nih.gov/pubmed/6262796
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