Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury

BACKGROUND: Burn survivors develop long-term cognitive impairment with increased inflammation and apoptosis in the brain. Gelsolin, an actin-binding protein with capping and severing activities, plays a crucial role in the septic response. We investigated if gelsolin infusion could attenuate neural...

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Detalhes bibliográficos
Main Authors: Zhang, Qing-Hong, Chen, Qi, Kang, Jia-Rui, Liu, Chen, Dong, Ning, Zhu, Xiao-Mei, Sheng, Zhi-Yong, Yao, Yong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191361/
https://ncbi.nlm.nih.gov/pubmed/21936896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-118
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