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Lens transglutaminase and cataract formation.

A protein polymer characteristically present in human cataract was shown to contain significant amounts of gamma-glutamyl-epsilon-lysine isopeptides. It is proposed that these crosslinks are produced by the action of transglutaminase (R-glutaminyl-peptide:amine-gamma-glutamyl-yltransferase, EC 2.3.2...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lorand, L, Hsu, L K, Siefring, G E, Rafferty, N S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319129/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6112745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1356
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