Decreased FMRP Expression Underlies Amygdala Dysfunction in Carriers of the Fragile X Premutation

BACKGROUND: The fragile X premutation provides a unique opportunity for the study of genetic and brain mechanisms of behavior and cognition in the context of neurodevelopment and neurodegeneration. Although the neurodegenerative phenotype, fragile X-associated tremor/ataxia syndrome (FXTAS), is well...

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Detalhes bibliográficos
Main Authors: Hessl, David, Wang, John M., Schneider, Andrea, Koldewyn, Kami, Le, Lien, Iwahashi, Christine, Cheung, Katherine, Tassone, Flora, Hagerman, Paul J., Rivera, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191264/
https://ncbi.nlm.nih.gov/pubmed/21783174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.05.033
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