Cellular Stress Induced Alterations in MicroRNA let-7a and let-7b Expression Are Dependent on p53

Genotoxic stressors, such as radiation, induce cellular damage that activates pre-programmed repair pathways, some of which involve microRNAs (miRNA) that alter gene expression. The let-7 family of miRNA regulates multiple cellular processes including cell division and DNA repair pathways. However,...

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Detalhes bibliográficos
Main Authors: Saleh, Anthony D., Savage, Jason E., Cao, Liu, Soule, Benjamin P., Ly, David, DeGraff, William, Harris, Curtis C., Mitchell, James B., Simone, Nicole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191136/
https://ncbi.nlm.nih.gov/pubmed/22022355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024429
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