Aurora-A Phosphorylates Augmin Complex Component Hice1 Protein at an N-terminal Serine/Threonine Cluster to Modulate Its Microtubule Binding Activity during Spindle Assembly

Proper assembly of mitotic spindles requires Hice1, a spindle-associated protein. Hice1 possesses direct microtubule binding activity at its N-terminal region and contributes to intraspindle microtubule nucleation as a subunit of the Augmin complex. However, whether microtubule binding activity of H...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tsai, Connie Y., Ngo, Bryan, Tapadia, Anjali, Hsu, Pang-Hung, Wu, Guikai, Lee, Wen-Hwa
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191049/
https://ncbi.nlm.nih.gov/pubmed/21705324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266767
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares