The Tumor Suppressor Hamartin Enhances Dbl Protein Transforming Activity through Interaction with Ezrin

The Rho guanine nucleotide exchange factor (GEF) Dbl binds to the N-terminal region of ezrin, a member of the ERM (ezrin, radixin, moesin) proteins known to function as linkers between the plasma membrane and the actin cytoskeleton. Here we have characterized the interaction between ezrin and Dbl. W...

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Detalhes bibliográficos
Main Authors: Ognibene, Marzia, Vanni, Cristina, Segalerba, Daniela, Mancini, Patrizia, Merello, Elisa, Torrisi, Maria Rosaria, Bosco, Maria Carla, Varesio, Luigi, Eva, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191038/
https://ncbi.nlm.nih.gov/pubmed/21712385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.270785
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