Gain in Transcriptional Activity by Primate-specific Coevolution of Melanoma Antigen-A11 and Its Interaction Site in Androgen Receptor

Male sex development and growth occur in response to high affinity androgen binding to the androgen receptor (AR). In contrast to complete amino acid sequence conservation in the AR DNA and ligand binding domains among mammals, a primate-specific difference in the AR NH(2)-terminal region that regul...

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Bibliografiske detaljer
Main Authors: Liu, Qiang, Su, Shifeng, Blackwelder, Amanda J., Minges, John T., Wilson, Elizabeth M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191036/
https://ncbi.nlm.nih.gov/pubmed/21730049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244715
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