Morphine Withdrawal Stress Modulates Lipopolysaccharide-induced Interleukin 12 p40 (IL-12p40) Expression by Activating Extracellular Signal-regulated Kinase 1/2, Which Is Further Potentiated by Glucocorticoids

Withdrawal stress is a common occurrence in opioid users, yet very few studies have examined the effects of morphine withdrawal (MW) on immune functioning or the role of glucocorticoids in MW-induced immunomodulation. This study investigated for the first time the role of glucocorticoids in MW modul...

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Hlavní autoři: Das, Subhas, Kelschenbach, Jennifer, Charboneau, Richard, Barke, Roderick A., Roy, Sabita
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191022/
https://ncbi.nlm.nih.gov/pubmed/21730055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.271460
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