Interleukin-1 Activates Synthesis of Interleukin-6 by Interfering with a KH-type Splicing Regulatory Protein (KSRP)-dependent Translational Silencing Mechanism

Post-transcriptional mechanisms play an important role in the control of inflammatory gene expression. The heterogeneous nuclear ribonucleoprotein K homology (KH)-type splicing regulatory protein (KSRP) triggers rapid degradation of mRNAs for various cytokines, chemokines, and other inflammation-rel...

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Detalhes bibliográficos
Main Authors: Dhamija, Sonam, Kuehne, Nancy, Winzen, Reinhard, Doerrie, Anneke, Dittrich-Breiholz, Oliver, Thakur, Basant Kumar, Kracht, Michael, Holtmann, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190945/
https://ncbi.nlm.nih.gov/pubmed/21795706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264754
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