Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin

Protein kinase D (PKD) is a nodal point in cardiac hypertrophic signaling. It triggers nuclear export of class II histone deacetylase (HDAC) and regulates transcription. Although this pathway is thought to be critical in cardiac hypertrophy and heart failure, little is known about spatiotemporal asp...

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Main Authors: Bossuyt, Julie, Chang, Chia-Wei, Helmstadter, Kathryn, Kunkel, Maya T., Newton, Alexandra C., Campbell, Kenneth S., Martin, Jody L., Bossuyt, Sven, Robia, Seth L., Bers, Donald M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190922/
https://ncbi.nlm.nih.gov/pubmed/21795686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246447
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