Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin

Protein kinase D (PKD) is a nodal point in cardiac hypertrophic signaling. It triggers nuclear export of class II histone deacetylase (HDAC) and regulates transcription. Although this pathway is thought to be critical in cardiac hypertrophy and heart failure, little is known about spatiotemporal asp...

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Главные авторы: Bossuyt, Julie, Chang, Chia-Wei, Helmstadter, Kathryn, Kunkel, Maya T., Newton, Alexandra C., Campbell, Kenneth S., Martin, Jody L., Bossuyt, Sven, Robia, Seth L., Bers, Donald M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190922/
https://ncbi.nlm.nih.gov/pubmed/21795686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246447
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