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Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin
Protein kinase D (PKD) is a nodal point in cardiac hypertrophic signaling. It triggers nuclear export of class II histone deacetylase (HDAC) and regulates transcription. Although this pathway is thought to be critical in cardiac hypertrophy and heart failure, little is known about spatiotemporal asp...
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主要な著者: | , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Biochemistry and Molecular Biology
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190922/ https://ncbi.nlm.nih.gov/pubmed/21795686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246447 |
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