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Biochemical Basis of Asthma Therapy

Current therapy for asthma is highly effective. β(2)-Adrenergic receptor (β(2)AR) agonists are the most effective bronchodilators and relax airway smooth muscle cells through increased cAMP concentrations and directly opening large conductance Ca(2+) channels. β(2)AR may also activate alternative si...

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Bibliographic Details
Main Author: Barnes, Peter J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190895/
https://ncbi.nlm.nih.gov/pubmed/21799015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.206466
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