Full-length Dengue Virus RNA-dependent RNA Polymerase-RNA/DNA Complexes: STOICHIOMETRIES, INTRINSIC AFFINITIES, COOPERATIVITIES, BASE, AND CONFORMATIONAL SPECIFICITIES

Fundamental aspects of interactions of the Dengue virus type 3 full-length polymerase with the single-stranded and double-stranded RNA and DNA have been quantitatively addressed. The polymerase exists as a monomer with an elongated shape in solution. In the absence of magnesium, the total site size...

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Detalhes bibliográficos
Main Authors: Szymanski, Michal R., Jezewska, Maria J., Bujalowski, Paul J., Bussetta, Cecile, Ye, Mengyi, Choi, Kyung H., Bujalowski, Wlodzimierz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190876/
https://ncbi.nlm.nih.gov/pubmed/21725087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255034
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