Impaired α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Trafficking and Function by Mutant Huntingtin

Emerging evidence from studies of Huntington disease (HD) pathophysiology suggests that huntingtin (htt) and its associated protein HAP1 participate in intracellular trafficking and synaptic function. However, it is largely unknown whether AMPA receptor trafficking, which is crucial for controlling...

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Detalhes bibliográficos
Main Authors: Mandal, Madhuchhanda, Wei, Jing, Zhong, Ping, Cheng, Jia, Duffney, Lara J., Liu, Wenhua, Yuen, Eunice Y., Twelvetrees, Alison E., Li, Shihua, Li, Xiao-Jiang, Kittler, Josef T., Yan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190808/
https://ncbi.nlm.nih.gov/pubmed/21832090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236521
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