Impaired α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Trafficking and Function by Mutant Huntingtin

Emerging evidence from studies of Huntington disease (HD) pathophysiology suggests that huntingtin (htt) and its associated protein HAP1 participate in intracellular trafficking and synaptic function. However, it is largely unknown whether AMPA receptor trafficking, which is crucial for controlling...

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Hlavní autoři: Mandal, Madhuchhanda, Wei, Jing, Zhong, Ping, Cheng, Jia, Duffney, Lara J., Liu, Wenhua, Yuen, Eunice Y., Twelvetrees, Alison E., Li, Shihua, Li, Xiao-Jiang, Kittler, Josef T., Yan, Zhen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190808/
https://ncbi.nlm.nih.gov/pubmed/21832090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236521
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