The Chlamydia Effector Chlamydial Outer Protein N (CopN) Sequesters Tubulin and Prevents Microtubule Assembly

Chlamydia species are obligate intracellular pathogens that utilize a type three secretion system to manipulate host cell processes. Genetic manipulations are currently not possible in Chlamydia, necessitating study of effector proteins in heterologous expression systems and severely complicating ef...

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Autors principals: Archuleta, Tara L., Du, Yaqing, English, Chauca A., Lory, Stephen, Lesser, Cammie, Ohi, Melanie D., Ohi, Ryoma, Spiller, Benjamin W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190796/
https://ncbi.nlm.nih.gov/pubmed/21841198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258426
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