Role of Extracellular Matrix Renal Tubulo-interstitial Nephritis Antigen (TINag) in Cell Survival Utilizing Integrin αvβ3/Focal Adhesion Kinase (FAK)/Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B-Serine/Threonine Kinase (AKT) Signaling Pathway

Tubulo-interstitial nephritis antigen (TINag) is an extracellular matrix protein expressed in tubular basement membranes. Combined mutations in TINag and nephrocystin-1 genes lead to nephronophthisis with reduced cell survival. Because certain extracellular matrix proteins are known to modulate cell...

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Main Authors: Xie, Ping, Kondeti, Vinay K., Lin, Sun, Haruna, Yoshisuke, Raparia, Kirtee, Kanwar, Yashpal S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190785/
https://ncbi.nlm.nih.gov/pubmed/21795690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241778
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