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Angiopoietin-2, an Angiogenic Regulator, Promotes Initial Growth and Survival of Breast Cancer Metastases to the Lung through the Integrin-linked Kinase (ILK)-AKT-B Cell Lymphoma 2 (Bcl-2) Pathway

The early onsets of breast cancer metastasis involve cell retention, survival, and resistant to apoptosis and subsequent growth at target vascular beds and tissues in distant organs. We previously reported that angiopoietin-2 (Ang2), an angiogenic regulator stimulates MCF-7 breast tumor metastasis f...

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Hlavní autoři: Imanishi, Yorihisa, Hu, Bo, Xiao, Gutian, Yao, Xuebiao, Cheng, Shi-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190731/
https://ncbi.nlm.nih.gov/pubmed/21680733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.235689
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