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Site-1 Protease Is Essential to Growth Plate Maintenance and Is a Critical Regulator of Chondrocyte Hypertrophic Differentiation in Postnatal Mice

Site-1 protease (S1P) is a proprotein convertase with essential functions in lipid homeostasis and unfolded protein response pathways. We previously studied a mouse model of cartilage-specific knock-out of S1P in chondroprogenitor cells. These mice exhibited a defective cartilage matrix devoid of ty...

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מידע ביבליוגרפי
Main Authors: Patra, Debabrata, DeLassus, Elizabeth, Hayashi, Shinya, Sandell, Linda J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190729/
https://ncbi.nlm.nih.gov/pubmed/21652717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208686
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