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Investigation of the Molecular Origins of Protein-arginine Methyltransferase I (PRMT1) Product Specificity Reveals a Role for Two Conserved Methionine Residues

Protein-arginine methyltransferases aid in the regulation of many biological processes by methylating specific arginyl groups within targeted proteins. The varied nature of the response to methylation is due in part to the diverse product specificity displayed by the protein-arginine methyltransfera...

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Detalhes bibliográficos
Main Authors: Gui, Shanying, Wooderchak, Whitney L., Daly, Michael P., Porter, Paula J., Johnson, Sean J., Hevel, Joan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190719/
https://ncbi.nlm.nih.gov/pubmed/21697082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224097
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