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Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae.

Carboxypeptidase Y, a vacuolar enzyme in Saccharomyces cerevisiae, is synthesized as a larger precursor whose apparent molecular mass is approximately 67,000 daltons. We have characterized a recessive mutation, pep4-3, that prevents maturation of this precursor. The accumulated precursor does not po...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hemmings, B A, Zubenko, G S, Hasilik, A, Jones, E W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.435
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