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Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

Intravenous (IV) stem cell delivery for regenerative tissue therapy has been increasingly used in both experimental and clinical trials. However, recent data suggest that the majority of administered stem cells are initially trapped in the lungs. We sought to investigate variables that may affect th...

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Autores principales: Fischer, Uwe M., Harting, Matthew T., Jimenez, Fernando, Monzon-Posadas, Werner O., Xue, Hasen, Savitz, Sean I., Laine, Glen A., Cox, Charles S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190292/
https://ncbi.nlm.nih.gov/pubmed/19099374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2008.0253
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