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Mechanism of mRNA capping by vaccinia virus guanylyltransferase: characterization of an enzyme--guanylate intermediate.

Vaccinia virus RNA guanylyltransferase catalyzes the transfer of GMP from GTP to the 5'-triphosphate or diphosphate terminus of RNA to generate the cap structure G(5')ppp(5')N-. The guanylylation reaction consists of a series of at least two partial reactions: (i) GTP + E in equilibri...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Shuman, S, Hurwitz, J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264433/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.187
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