Computational design and selections for an engineered, thermostable terpene synthase

Terpenoids include structurally diverse antibiotics, flavorings, and fragrances. Engineering terpene synthases for control over the synthesis of such compounds represents a long sought goal. We report computational design, selections, and assays of a thermostable mutant of tobacco 5-epi-aristolochen...

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Main Authors: Diaz, Juan E, Lin, Chun-Shi, Kunishiro, Kazuyoshi, Feld, Birte K, Avrantinis, Sara K, Bronson, Jonathan, Greaves, John, Saven, Jeffery G, Weiss, Gregory A
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190154/
https://ncbi.nlm.nih.gov/pubmed/21739507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.691
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