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Fibrinogen alters mouse brain endothelial cell layer integrity affecting vascular endothelial cadherin
Many inflammatory diseases are associated with elevated blood concentration of fibrinogen (Fg) leading to vascular dysfunction. We showed that pathologically high (4 mg/ml) content of Fg disrupts integrity of endothelial cell (EC) layer and causes macromolecular leakage affecting tight junction prot...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190052/ https://ncbi.nlm.nih.gov/pubmed/21920349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.07.133 |
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