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Functional changes in postsynaptic adenosine A(2A) receptors during early stages of a rat model of Huntington disease

Huntington disease (HD) is a neurodegenerative disorder involving preferential loss of striatal GABAergic medium spiny neurons. Adenosine A(2A) receptors (A(2A)Rs) are present in the striatum at both presynaptic and post-synaptic levels. Blocking pre-synaptic A(2A)Rs, localized in glutamatergic term...

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Main Authors: Orrú, Marco, Zanoveli, Janaina, Quiroz, César, Nguyen, Huu Phuc, Guitart, Xavier, Ferré, Sergi
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190040/
https://ncbi.nlm.nih.gov/pubmed/21867705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.08.005
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