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Specific phospholipids are required to reconstitute adenylate cyclase solubilized from rat brain.

Adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] was solubilized from a rat brain homogenate with sodium deoxycholate. This solubilized preparation had no detectable enzymic activity with either Mg-ATP or Mn-ATP as substrate. The activity could be restored by addition of either no...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hebdon, G M, LeVine, H, Sahyoun, N E, Schmitges, C J, Cuatrecasas, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6941240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.120
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