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Ebola Virus Enters Host Cells by Macropinocytosis and Clathrin-Mediated Endocytosis

Virus entry into host cells is the first step of infection and a crucial determinant of pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the glycoprotein GP(1,2) and the matrix protein VP40 use macropinocytosis and clathrin-mediated endocytosis to enter cells. EBOV...

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Detalhes bibliográficos
Main Authors: Aleksandrowicz, Paulina, Marzi, Andrea, Biedenkopf, Nadine, Beimforde, Nadine, Becker, Stephan, Hoenen, Thomas, Feldmann, Heinz, Schnittler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189988/
https://ncbi.nlm.nih.gov/pubmed/21987776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir326
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