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High-Density Real-Time PCR-Based in Vivo Toxicogenomic Screen to Predict Organ-Specific Toxicity

Toxicogenomics, based on the temporal effects of drugs on gene expression, is able to predict toxic effects earlier than traditional technologies by analyzing changes in genomic biomarkers that could precede subsequent protein translation and initiation of histological organ damage. In the present s...

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Bibliographische Detailangaben
Hauptverfasser: Fabian, Gabriella, Farago, Nora, Feher, Liliana Z., Nagy, Lajos I., Kulin, Sandor, Kitajka, Klara, Bito, Tamas, Tubak, Vilmos, Katona, Robert L., Tiszlavicz, Laszlo, Puskas, Laszlo G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189772/
https://ncbi.nlm.nih.gov/pubmed/22016648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12096116
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