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Calcium Modulated Chloride Pathways Contribute to Chloride Flux in Murine CF-Affected Macrophages

Cystic Fibrosis (CF), a common lethal inherited disorder defined by ion transport abnormalities, chronic infection and robust inflammation, is the result of mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a cAMP-activated chloride (Cl(−)) channe...

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Main Authors: Shenoy, Ambika, Kopic, Sascha, Murek, Michael, Caputo, Christina, Geibel, John P., Egan, Marie E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189336/
https://ncbi.nlm.nih.gov/pubmed/21796019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31822f2448
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