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Effects of Zinc Deuteroporphyrin Bis Glycol on Newborn Mice After Heme-Loading

Infants with hemolytic diseases frequently develop hyperbilirubinemia, but standard phototherapy only eliminates bilirubin after its production. A better strategy might be to directly inhibit heme oxygenase (HO), the rate-limiting enzyme in bilirubin production. Metalloporphyrins (Mps) are heme anal...

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Detalhes bibliográficos
Main Authors: He, Cynthia X., Campbell, Claire M., Zhao, Hui, Kalish, Flora S., Schulz, Stephanie, Vreman, Hendrik J., Wong, Ronald J., Stevenson, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189293/
https://ncbi.nlm.nih.gov/pubmed/21785387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31822e1675
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