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RNA polymerase activity and template activity of chromatin after butyrate induced hyperacetylation of histones in Physarum.

We have studied the effect of sodium-n-butyrate on endogenous RNA polymerase in Physarum polycephalum. 1 mM butyrate strongly reduces RNA polymerase activity measured in isolated nuclei or chromatin; both RNA polymerase A as well as the alpha-amanitin sensitive RNA polymerase B are equally affected....

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Detalhes bibliográficos
Main Authors: Loidl, P, Loidl, A, Puschendorf, B, Gröbner, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC318927/
https://ncbi.nlm.nih.gov/pubmed/6462909
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