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Replication initiation at the Escherichia coli chromosomal origin

To initiate DNA replication, DnaA recognizes and binds to specific sequences within the Escherichia coli chromosomal origin (oriC), and then unwinds a region within oriC. Next, DnaA interacts with DnaB helicase in loading the DnaB-DnaC complex on each separated strand. Primer formation by primase (D...

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Bibliographic Details
Main Author: Kaguni, Jon M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189269/
https://ncbi.nlm.nih.gov/pubmed/21856207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2011.07.016
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