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Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells

The bone marrow microenvironment facilitates the survival, differentiation, and proliferation of myeloma (MM) cells. This study identified that microRNA-15a and -16 expressions tightly correlated with proliferation and drug sensitivity of MM cells. miRNA-15a/-16 expression in MM cells was significan...

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Detalhes bibliográficos
Main Authors: Hao, Mu, Zhang, Li, An, Gang, Sui, Weiwei, Yu, Zhen, Zou, Dehui, Xu , Yan, Chang, Hong, Qiu, Lugui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189173/
https://ncbi.nlm.nih.gov/pubmed/21936961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-37
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