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HSP90 functions in the circadian clock through stabilization of the client F-box protein ZEITLUPE

The autoregulatory loops of the circadian clock consist of feedback regulation of transcription/translation circuits but also require finely coordinated cytoplasmic and nuclear proteostasis. Although protein degradation is important to establish steady-state levels, maturation into their active conf...

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Bibliographic Details
Main Authors: Kim, Tae-sung, Kim, Woe Yeon, Fujiwara, Sumire, Kim, Jeongsik, Cha, Joon-Yung, Park, Jin Ho, Lee, Sang Yeol, Somers, David E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189077/
https://ncbi.nlm.nih.gov/pubmed/21949396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110406108
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