Frequency of Nonallelic Homologous Recombination Is Correlated with Length of Homology: Evidence that Ectopic Synapsis Precedes Ectopic Crossing-Over

Genomic disorders constitute a class of diseases that are associated with DNA rearrangements resulting from region-specific genome instability, that is, genome architecture incites genome instability. Nonallelic homologous recombination (NAHR) or crossing-over in meiosis between sequences that are n...

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Detalhes bibliográficos
Main Authors: Liu, Pengfei, Lacaria, Melanie, Zhang, Feng, Withers, Marjorie, Hastings, P.J., Lupski, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188830/
https://ncbi.nlm.nih.gov/pubmed/21981782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.09.009
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