Protoporphyrin IX fluorescence contrast in invasive glioblastomas is linearly correlated with Gd enhanced magnetic resonance image contrast but has higher diagnostic accuracy

The sensitivity and specificity of in vivo magnetic resonance (MR) imaging is compared with production of protoporphyrin IX (PpIX), determined ex vivo, in a diffusely infiltrating glioma. A human glioma transfected with green fluorescent protein, displaying diffuse, infiltrative growth, was implante...

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Detalhes bibliográficos
Main Authors: Samkoe, Kimberley S., Gibbs-Strauss, Summer L., Yang, Harold H., Khan Hekmatyar, S., Jack Hoopes, P., O’Hara, Julia A., Kauppinen, Risto A., Pogue, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers (SPIE) 2011
Assuntos:
Research Papers: Imaging
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188641/
https://ncbi.nlm.nih.gov/pubmed/21950922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3622754
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