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Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms

BACKGROUND: A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identical by descent) on phenotypes. However, it is unknown which current ROH detection...

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Detaylı Bibliyografya
Asıl Yazarlar: Howrigan, Daniel P, Simonson, Matthew A, Keller, Matthew C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188534/
https://ncbi.nlm.nih.gov/pubmed/21943305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-460
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