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Post-natal Effect of Overexpressed DKK1 on Mandibular Molar Formation
Dickkopf-related protein 1 (DKK1) is a potent inhibitor of Wnt/β-catenin signaling. Dkk1-null mutant embryos display severe defects in head induction. Conversely, targeted expression of Dkk1 in dental epithelial cells leads to the formation of dysfunctional enamel knots and subsequent tooth defects...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188462/ https://ncbi.nlm.nih.gov/pubmed/21917600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034511421926 |
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