Evidence for two independent prostate cancer risk associated loci in the HNF1B gene at 17q12

A fine mapping study in the HNF1B gene at 17q12 among two study populations revealed a second prostate cancer locus, ~26 kb centromeric to the first known locus (rs4430796); these are separated by a recombination hotspot. A SNP in the second locus (rs11649743) was confirmed in five additional popula...

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Detalhes bibliográficos
Main Authors: Sun, Jielin, Zheng, Siqun Lilly, Wiklund, Fredrik, Isaacs, Sarah D., Li, Ge, Hsu, Fang-Chi, Kim, Seong-Tae, Liu, Wennuan, Zhu, Yi, Stattin, Pär, Adami, Hans-Olov, Wiley, Kathleen E., Dimitrov, Latchezar, Sun, Jishan, Li, Tao, Turner, Aubrey R., Adams, Tamara S., Adolfsson, Jan, Johansson, Jan-Erik, Lowey, James, Trock, Bruce J., Partin, Alan W., Walsh, Patrick C., Trent, Jeffrey M, Duggan, David, Carpten, John, Chang, Bao-Li, Grönberg, Henrik, Isaacs, William B., Xu, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188432/
https://ncbi.nlm.nih.gov/pubmed/18758462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.214
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