Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy

OBJECTIVE: This study investigated a novel approach to induce chondrogenic differentiation of human mesenchymal stem cells (hMSC). We hypothesized that a structured three-dimensional co-culture using hMSC and chondrocytes would provide chondroinductive cues to hMSC without inducing hypertrophy. METH...

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Detalhes bibliográficos
Main Authors: Cooke, ME, Allon, AA, Cheng, T, Kuo, AC, Kim, HT, Vail, TP, Marcucio, RS, Schneider, RA, Lotz, JC, Alliston, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188316/
https://ncbi.nlm.nih.gov/pubmed/21816228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2011.07.005
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