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Assembly of functional antibodies from immunoglobulin heavy and light chains synthesised in E. coli.

Genes for a murine mu heavy chain and a lambda light chain immunoglobulin have been inserted into bacterial expression plasmids containing the Escherichia coli trp promoter and ribosome binding site. Induction of transcription from the trp promoter results in accumulation of both light and heavy cha...

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Detalhes bibliográficos
Main Authors: Boss, M A, Kenten, J H, Wood, C R, Emtage, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC318790/
https://ncbi.nlm.nih.gov/pubmed/6328437
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