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A Clonal Group of Nontypeable Haemophilus influenzae with Two IgA Proteases Is Adapted to Infection in Chronic Obstructive Pulmonary Disease

Strains of nontypeable Haemophilus influenzae show enormous genetic heterogeneity and display differential virulence potential in different clinical settings. The igaB gene, which encodes a newly identified IgA protease, is more likely to be present in the genome of COPD strains of H. influenzae tha...

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Autors principals: Murphy, Timothy F., Lesse, Alan J., Kirkham, Charmaine, Zhong, Huachun, Sethi, Sanjay, Munson, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187821/
https://ncbi.nlm.nih.gov/pubmed/21998721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025923
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