A Clonal Group of Nontypeable Haemophilus influenzae with Two IgA Proteases Is Adapted to Infection in Chronic Obstructive Pulmonary Disease

Strains of nontypeable Haemophilus influenzae show enormous genetic heterogeneity and display differential virulence potential in different clinical settings. The igaB gene, which encodes a newly identified IgA protease, is more likely to be present in the genome of COPD strains of H. influenzae tha...

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Bibliographic Details
Main Authors: Murphy, Timothy F., Lesse, Alan J., Kirkham, Charmaine, Zhong, Huachun, Sethi, Sanjay, Munson, Robert S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187821/
https://ncbi.nlm.nih.gov/pubmed/21998721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025923
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