Localization of CD4(+) T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing

The spectrum of immunogenic epitopes presented by the H2-IA(b) MHC class II molecule to CD4(+) T cells has been defined for two different (clade B and clade D) HIV envelope (gp140) glycoproteins. Hybridoma T cell lines were generated from mice immunized by a sequential prime and boost regime with DN...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Surman, Sherri, Lockey, Timothy D., Slobod, Karen S., Jones, Bart, Riberdy, Janice M., White, Stephen W., Doherty, Peter C., Hurwitz, Julia L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071063898
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