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Implementing Prenatal Diagnosis Based on Cell-Free Fetal DNA: Accurate Identification of Factors Affecting Fetal DNA Yield

OBJECTIVE: Cell-free fetal DNA is a source of fetal genetic material that can be used for non-invasive prenatal diagnosis. Usually constituting less than 10% of the total cell free DNA in maternal plasma, the majority is maternal in origin. Optimizing conditions for maximizing yield of cell-free fet...

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Autors principals: Barrett, Angela N., Zimmermann, Bernhard G., Wang, Darrell, Holloway, Andrew, Chitty, Lyn S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187716/
https://ncbi.nlm.nih.gov/pubmed/21998643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025202
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