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Improving Liquid Chromatography-Mass Spectrometry Sensitivity Using a Subambient Pressure Ionization with Nanoelectrospray (SPIN) Interface

In this work, the subambient pressure ionization with nanoelectrospray (SPIN) ion source and interface, which operates at ~15–30 Torr, is demonstrated to be compatible with gradient reversed-phase liquid chromatography-MS applications, exemplified here with the analysis of complex samples (a protein...

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Main Authors: Tang, Keqi, Page, Jason S., Marginean, Ioan, Kelly, Ryan T., Smith, Richard D.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187566/
https://ncbi.nlm.nih.gov/pubmed/21953185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0135-7
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