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Bioorthogonal Probes for Polo-Like Kinase 1 Imaging and Quantification

[Image: see text] A nuclear protein target, polo-like kinase 1 (PLK1) was imaged using a biocompatible bioorthogonal ligation between a specific drug and a fluorescent dye in live cells. Colocalization of the dye and the protein target was confirmed by antibody staining and by expressing a GFP const...

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Detalhes bibliográficos
Main Authors: Budin, Ghyslain, Yang, Katherine S., Reiner, Thomas, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187564/
https://ncbi.nlm.nih.gov/pubmed/21948435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201103273
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