Mapping of psoralen cross-linked nucleotides in RNA.

A method is described for using the cross-linking reagent 4'-(hydroxy-methyl)-4,5',8-trimethylpsoralen (HMT) to map base paired regions and higher-order structure within RNA molecules. Applying this method to yeast tRNAPhe, we have specifically identified cross-links within the acceptor st...

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Bibliographic Details
Main Authors: Garrett-Wheeler, E, Lockard, R E, Kumar, A
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC318754/
https://ncbi.nlm.nih.gov/pubmed/6425802
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