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De Novo Infection of B Cells during Murine Gammaherpesvirus 68 Latency

The mechanisms by which gammaherpesviruses maintain latency are unclear. Here we used a murine gammaherpesvirus model to show that previously uninfected B cells in immunocompetent mice can acquire virus during latency. In vivo depletion of T cells allowed viral reactivation, as measured by increased...

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Bibliografiske detaljer
Main Authors: Freeman, Michael L., Burkum, Claire E., Yager, Eric J., Woodland, David L., Blackman, Marcia A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187493/
https://ncbi.nlm.nih.gov/pubmed/21849446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05027-11
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